Healthy volunteers and early phases of clinical experimentation
نویسندگان
چکیده
منابع مشابه
Effect of Nail Polish on Pulse Oximetry Findings in Healthy Volunteers: A Randomized Clinical Trail
Background and Objectives: Pulse oximetry is the most common technique for monitoring hemoglobin oxygen saturation (SpO2). Different colors and brands of nail polish may cause disturbance in the reading and interpretation of oxygen saturation. The aim of this study was to determine the effect of different colors of nail polish on oxygen saturation measured by pulse oximeter. Methods: Thirty he...
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BACKGROUND Inhalation of endotoxin (LPS) induces a predominantly neutrophilic airway inflammation and has been used as model to test the anti-inflammatory activity of novel drugs. In the past, a dose exceeding 15-50 μg was generally needed to induce a sufficient inflammatory response. For human studies, regulatory authorities in some countries now request the use of GMP-grade LPS, which is of l...
متن کاملPhase I Clinical Study of Edaravone in Healthy Chinese Volunteers
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ژورنال
عنوان ژورنال: European Journal of Clinical Pharmacology
سال: 2010
ISSN: 0031-6970,1432-1041
DOI: 10.1007/s00228-010-0827-0